Mushroom spores are the microscopic reproductive cells that allow fungi to reproduce and spread. In mushroom cultivation, spores are the starting point for growing new strains. When germinated under sterile conditions, they form mycelium — the root-like network that eventually produces mushrooms. Understanding how to work with spores is essential for any successful cultivator.

Yes, in most U.S. states, mushroom spores are legal to buy and possess for microscopy and educational purposes since they do not contain psilocybin. However, it’s important to check your state laws before purchasing, as a few states — such as California, Georgia, and Idaho — have restrictions on spore sales.

Mushroom spores are the genetic blueprint, while liquid culture contains living mycelium that has already grown from those spores. Spores are best for learning genetics and strain variation, while liquid culture offers faster and more reliable colonization for growers looking to save time.

Spores should be kept in a cool, dark, and dry environment to preserve viability. The ideal storage method is inside a sealed spore syringe or print, placed in a refrigerator (around 35–45°F). Proper storage ensures the spores remain viable for microscopic study or future cultivation research.